中国循证医学杂志

中国循证医学杂志

GRADE 在动物实验系统评价中的应用与挑战

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动物实验系统评价证据体的分级评价,有助于提高动物实验结果向临床试验和临床实践转化的可行性,高质量的动物实验证据更有可能作为可靠证据来支持进行下一步的临床研究(即更强的转化信心)和突发公共事件的卫生决策。本研究将详细介绍 GRADE 在动物实验系统评价中应用的原理、方法和面临的挑战。

Grading the evidence of systematic reviews on animal studies will contribute to the improvement in the feasibility of transforming the results of animal studies into clinical trials or clinical practice. High quality evidence from animal studies is more likely to be successfully applied into clinical practice (i.e. more confident). Therefore, the present study will introduce the principles, methods and challenges of the application of GRADE in systematic reviews on animal studies.

关键词: GRADE; 动物实验系统评价; 应用

Key words: GRADE; Systematic reviews of animal studies; Application

引用本文: 张婷, 王欢, 邢丹, 陈耀龙, 邝心颖, 陈昊, 姜彦彪, 胡凯燕, 马彬. GRADE 在动物实验系统评价中的应用与挑战. 中国循证医学杂志, 2019, 19(2): 248-252. doi: 10.7507/1672-2531.201809068 复制

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