中国循证医学杂志

中国循证医学杂志

混合方法研究在真实世界研究中的应用

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混合方法研究(mixed methods research,MMR)是将定量与定性研究这两大主要研究范式有机结合的第三种研究范式。MMR 规范有序地在一个研究或项目中使用定性和定量方法收集和分析数据,通过整合优势克服定性和定量方法各自的局限来生产高质量的研究证据。而真实世界研究的环境较复杂,在使用真实世界数据评估患者健康状况、疾病及诊疗过程、防治结局、患者预后与预测、或者支持医疗政策制定时,应用 MMR,可在一定程度上更全面地回答研究问题,从而提高研究真实性和准确性。

Mixed methods research (MMR) is the third research paradigm that combines quantitative and qualitative research. MMR can overcome limitations of qualitative and quantitative methods by integrating the advantages of these two. The environment of real world research is complicated. When using real world data to assess the health status of patients, process of treatment, outcomes of prevention and treatment, prognosis and prediction, and support for medical policy development, MMR can be applied to tackle research questions more comprehensively for the quality of research.

关键词: 混合方法研究; 真实世界研究; 临床研究

Key words: Mixed methods research; Real world study; Clinical research

引用本文: 褚红玲, 倪凯文, 曾琳, 李楠, MichaelD. Fetters, 陶立元, 石岩岩, 张华, 王晓晓, 赵一鸣. 混合方法研究在真实世界研究中的应用. 中国循证医学杂志, 2018, 18(11): 1203-1206. doi: 10.7507/1672-2531.201808035 复制

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