中国循证医学杂志

中国循证医学杂志

单病例随机对照试验的设计和实施要点

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单病例随机对照试验设计提供了一种方法来对单个患者的治疗进行最佳决策,本文简要介绍单病例随机对照设计的适用对象、实施过程以及临床实际应用,探讨单病例随机对照试验的设计和实施要点。

N-of-1 trial design offers a methodologically sound approach to determining optimum treatment for an individual patient and solves some limitations of randomized controlled trials. This design could offer an efficient method of reaching a personal treatment regime tailored to suit individual needs and preferences. The paper introduces practical application, objects and the implementation process of N-of-1 trial, to explore its design points and implementation.

关键词: 单病例随机对照; 设计; 实施; 应用

Key words: N-of-1 trial; Design; Implementation; Application

引用本文: 王辉, 翟静波, 陈静, 李江, 商洪才. 单病例随机对照试验的设计和实施要点. 中国循证医学杂志, 2017, 17(3): 364-368. doi: 10.7507/1672-2531.201701076 复制

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