中国循证医学杂志

中国循证医学杂志

国内医院药学人员发表系统评价/Meta 分析的文献计量学分析

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目的 对国内医院药学人员发表的系统评价/Meta 分析进行文献计量学分析和质量评价。 方法 计算机检索 CNKI、WanFang Data、VIP、CBM、CMCI、PubMed、EMbase、The Cochrane Library(2016 年 2 期)等数据库,检索时限均为建库到 2016 年 3 月 17 日。根据纳入与排除标准进行文献筛选和数据提取,采用 PRISMA 和 AMSTAR 分别进行报告质量和方法学质量评估,采用 Excel 2013 和 SPSS 20.0 软件进行数据统计分析。 结果 共纳入 1 018 篇系统评价/Meta 分析(中文 871 篇、英文 147 篇)。文献发表数量逐年增长,报告质量和研究质量呈现逐年增高趋势。纳入文献发表于《中国循证医学杂志》、《中国药房》等 146 种中文期刊和《PLoS One》等 97 种英文期刊;发文单位包括四川大学华西医院药剂科和北京大学第三医院药剂科等 308 家单位,分布于四川和北京等27个省市自治区。纳入研究主要评价了药物有效性与安全性评价,西药是药物评价的主要类别,抗肿瘤药是临床药物评价的重点。 结论 国内医院药学领域的循证药物评价发展迅速,质量呈现上升趋势,但各地展不均衡。

Objective To investigate the current status of systematic reviews/meta-analysis published by pharmacists in hospital in China by using bibliometric analysis and assess the methodological quality of these studies. Methods The literatures were searched from CNKI, WanFang Data, VIP, CBM, CMCI, PubMed, EMbase, The Cochrane Library (Issue 2, 2016) from the establish to March 17th, 2016. According to the inclusive and exclusive criteria, the authors independently screened literatures and extracted the data. Methodology quality and reporting quality were evaluated by using AMSTAR tool and PRIMSA statement. Data analyses were conducted by using Excel 2013 and SPSS 20.0 software. Results A total of 1018 systematic reviews/meta-analyses were included, 871 were published in Chinese language and 147 were in English language. The published literature increased year by year, as well as the reporting quality and methodological quality were increasing year by year. All of the included studies were published in 146 Chinese journals (includingChinese Journey of Evidence-Based Medicine andChina Pharmacy) and 97 English journals (includingPLoS One). The authors were from 308 hospitals, including Department of Pharmacy in West China Hospital of Sichuan University and Department of Pharmacy in Peking University Third Hospital; these studies were from 27 provinces, including Sichuan and Beijing. These studies evaluated the effectiveness and safety, western medicine were the main type, and anti-cancer drugs were main drugs of clinical evaluation. Conclusion Evidenced-based drug evaluation by hospital pharmacists in China is rapidly increasing as well as the methodological quality and reporting quality, however, the development is unbalanced in China.

关键词: 系统评价; Meta 分析; 药学人员; 文献计量学

Key words: Systematic reviews; Meta-analyses; Pharmacists; Bibliometric Analysis

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